Vegan Joint and Bone Support

Suitable For

Vegetarian

Vegan

No Gluten Containing Ingredients

No Nut Containing Ingredients

What is Metabolics Joint and Bone Support?

Metabolics Vegan Joint and Bone Support is a newly reformulated supplement designed to replace Metabolics Arthrolite, offering comprehensive bone and joint health support that is now suitable for vegans. This advanced formula combines powerful ingredients from our non-vegan Metabolics Jointmax with effective joint pain support components found in Metabolics Arthrolite, ensuring great nutritional support for your overall joint and bone health.

What is Metabolics Vegan Joint and Bone Support Good For?

Metabolics Vegan Joint and Bone Support is beneficial for maintaining healthy bones and joints, supporting issues such as joint pain and inflammation, and supporting the structural integrity of cartilage. It includes vitamin C for collagen formation, vitamin D for calcium absorption and bone mineralisation, manganese, which contributes to the normal formation of connective tissue, as well as the anti-inflammatory botanicals turmeric and ginger. The formula also contains vegan Glucosamine HCL, MSM (Methylsulfonylmethane), and hyaluronic acid, all known for playing crucial roles in supporting joint health and function.

Who is Metabolics Vegan Joint and Bone Support For?

This supplement is ideal for individuals seeking to support and maintain their joint and bone health. As we age, especially in women’s health, the risk of osteoporosis and joint-related issues increases due to hormonal changes that affect bone density and joint flexibility. Metabolics Vegan Joint and Bone Support offers nutritional support for those experiencing joint pain, stiffness, or inflammation, helping to support you with these age-related concerns. Additionally, as a vegan-friendly formula, it caters to individuals following a plant-based diet, ensuring they receive essential nutrients without compromising their dietary choices.

Why Use Metabolics Vegan Joint and Bone Support?

Using Metabolics Vegan Joint and Bone Support offers several benefits:

Support for your bone health

Metabolics Vegan Joint and Bone Support combines essential vitamins like Vitamin C, D, E, K, and minerals such as manganese and zinc to support bone density, strength, and overall health.

Vitamin C

Vitamin C is crucial for maintaining normal bones and forming collagen for healthy cartilage function. As a cofactor for collagen-synthesising enzymes, Vitamin C supports the creation of this key structural protein found in bones, cartilage, tendons, and skin. Collagen offers structural support and elasticity to these tissues, cushioning joints and ensuring their flexibility and range of motion. Vitamin C is essential for forming collagen fibres within cartilage, maintaining its structural integrity and resilience. It also promotes the production of osteoblasts, the cells responsible for bone formation, and enhances the absorption of calcium and other minerals vital for bone strength and density. Additionally, as an antioxidant, vitamin C protects bone and cartilage cells from oxidative stress and damage caused by free radicals, thereby supporting overall tissue health and function.

Vitamin D

Vitamin D is vital for bone health, playing multiple essential roles in maintaining the integrity and function of bones and joints. It enhances the absorption of calcium from the intestines into the bloodstream, a mineral crucial for bone strength and structure. Without adequate vitamin D, the body cannot effectively absorb calcium, leading to weakened bones and an increased risk of fractures. Vitamin D also promotes bone mineralisation by regulating the deposition of calcium and phosphorus into the bone matrix, which is critical for maintaining bone density and strength. Additionally, Vitamin D helps regulate bone remodelling—the continuous process of bone resorption and formation—by supporting the activity of osteoblasts (cells that build bone) and osteoclasts (cells that break down bone), ensuring optimal bone turnover and overall bone health.

Vitamin K

Vitamin K is crucial for bone health. It is essential for activating osteocalcin, a protein that binds calcium ions and helps incorporate them into bone mineral crystals. This process, known as bone mineralisation, is vital for maintaining bone density and strength. Additionally, Vitamin K supports bone remodelling by regulating the activity of osteoblasts (bone-building cells) and osteoclasts (bone-resorbing cells). Balanced bone remodelling ensures the replacement of old bone tissue with new bone tissue, maintaining bone health over time. At Metabolics, we use MenaQ7® (menaquinone-7, MK-7) as our preferred form of Vitamin K for its effectiveness and superior bioavailability.

Vitamin E

Vitamin E acts as a powerful antioxidant, neutralizing free radicals that can cause oxidative damage to cells, including those in bones and joints. By reducing oxidative stress, Vitamin E helps maintain healthy bone and joint tissues, contributing to overall tissue health and function.

Manganese

Manganese is a trace mineral essential for connective tissue and bone health. It serves as a cofactor for enzymes involved in synthesizing glycosaminoglycans, key components of connective tissues like cartilage and tendons. Manganese also supports collagen formation, a structural protein critical for the strength and elasticity of these tissues.

In addition, manganese contributes to bone mineralisation by activating enzymes that synthesise proteoglycans, proteins that help form the bone matrix. This process is crucial for maintaining bone density and strength. Manganese is also involved in producing manganese superoxide dismutase (MnSOD), an antioxidant enzyme that protects cells from oxidative stress, thereby helping to maintain the health of connective tissues and bones by reducing oxidative damage.

Zinc

Zinc is an essential mineral that supports overall health, particularly bone and joint function. It plays a key role in synthesising collagen, a protein crucial for providing structural support and flexibility to bone tissue. Collagen fibres help mineralise the bone matrix with calcium and other minerals, which is essential for maintaining bone strength and density.

Zinc is vital for bone healing and regeneration, promoting the activity of osteoblasts (the cells responsible for bone formation) and supporting the mineralisation of newly formed bone tissue during the healing process. Additionally, adequate zinc levels are necessary for proper immune support, which is important for maintaining joint health by supporting the immune response against infections and inflammation that can affect joints.

Support Joint Function

The formula also contains vegan Glucosamine HCL, MSM (Methylsulfonylmethane), and hyaluronic acid, all known for playing crucial roles in supporting joint health and function.

Glucosamine HCL

Glucosamine HCL is a naturally occurring compound found in cartilage, the tough tissue that cushions joints. Glucosamine HCL is a key building block of cartilage, the flexible connective tissue found in joints. It plays a crucial role in the synthesis of glycosaminoglycans and proteoglycans, which are essential components of cartilage. Healthy cartilage is vital for absorbing shock and reducing friction during movement.

MSM (Methylsulfonylmethane

MSM is a natural source of sulfur, an essential element involved in the formation of collagen, glucosamine, and chondroitin. Sulfur provided by MSM contributes to the structural integrity of cartilage. It supports the synthesis of collagen and keratin, which are important for the elasticity and strength of connective tissues, including cartilage, tendons, and ligaments.

Hyaluronic acid

Hyaluronic acid is a key component of synovial fluid, which lubricates and cushions joints. It helps reduce friction between bones during movement, promoting smooth and pain-free joint function. Hyaluronic acid is also found in high concentrations in cartilage, where it helps maintain its elasticity and ability to absorb shock.

Anti-inflammatory Support

Botanical extracts turmeric and ginger, are known for their powerful anti-inflammatory and antioxidant properties, to help manage joint pain and inflammation.

Turmeric (Curcuma longa)

Turmeric has a pending health claim for its role in maintaining joint and bone health and managing inflammatory responses. Its active component, curcumin, offers several benefits for joint pain management:

Curcumin inhibits key inflammatory pathways, such as the NF-kB pathway, which regulates the immune response to infection and inflammation. By blocking this pathway, curcumin reduces the production of pro-inflammatory cytokines.

Curcumin decreases the activity of enzymes like cyclooxygenase-2 (COX-2) and lipoxygenase, which are involved in the synthesis of inflammatory compounds called prostaglandins and leukotrienes.

Curcumin lowers the levels of various pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α), interleukin-1 (IL-1), and interleukin-6 (IL-6). These cytokines are signaling molecules that promote inflammation in the body.

Curcumin's antioxidant properties help neutralize free radicals, which can cause oxidative stress and trigger inflammatory responses. By reducing oxidative stress, curcumin helps mitigate inflammation.

NF-kB is a protein complex that controls DNA transcription, cytokine production, and cell survival. Curcumin inhibits NF-kB activation, reducing inflammation at the genetic level.

Curcumin promotes the production of anti-inflammatory proteins, which help counteract inflammation in the body.

By managing inflammatory processes, curcumin may help you with the pain and discomfort commonly associated with joint issues.

Ginger (Zingiber officinale)

Ginger is recognised for its potential to support joint mobility and reduce morning stiffness. It may help manage inflammatory responses and promote a normal balance of inflammatory hormones, such as prostaglandins. The active compounds in ginger, particularly gingerols, have potent anti-inflammatory effects:

Gingerols inhibit the production of pro-inflammatory cytokines and chemokines, key players in the inflammatory response.

Similar to curcumin in turmeric, ginger's active components inhibit cyclooxygenase (COX) and lipoxygenase (LOX) enzymes. This reduces the synthesis of inflammatory prostaglandins and leukotrienes, helping to decrease inflammation and associated pain.

Ginger reduces levels of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β), and interleukin-6 (IL-6). These cytokines contribute to joint pain and stiffness.

Ginger suppresses the activation of the nuclear factor kappa B (NF-κB) pathway, a key regulator of the inflammatory response.

Ginger has strong antioxidant properties that help neutralize free radicals, reducing oxidative stress and tissue damage, including in joint tissues. This action helps reduce inflammation and promotes joint health.

Ginger inhibits the production of nitric oxide, a free radical that contributes to inflammation and joint damage.

Ginger helps maintain a normal balance of inflammatory hormones, including prostaglandins, by modulating their synthesis. This helps control the inflammatory response and reduce joint pain and stiffness. As per EFSA ID 2649, ginger extract helps to maintain mobility of joints.

Maritime Pine Bark (pinus pinaster)

Maritime Pine Bark extract contains potent antioxidants, such as proanthocyanidins, which help neutralize free radicals. Free radicals cause oxidative stress, leading to cellular damage and inflammation, both of which are common sources of pain.

The compounds in pine bark extract help improve blood flow by strengthening capillaries and blood vessels. Better circulation means more efficient delivery of oxygen and nutrients to tissues, aiding in tissue repair.

Vegan-Friendly: Metabolics Vegan Joint and Bone Support is suitable for vegans, making it accessible to those following a plant-based diet.

For further bone health support, we recommend combining this supplement with a source of calcium and magnesium see Metabolics Calcium Magnesium Cit/Mal. This combination ensures a balanced intake of essential nutrients crucial for optimal bone health.